10. Titanium dioxide (a mineral mined from iron ore that is also used as a pigment for white paint) makes the crème filling white. I know, I know, we said there weren’t as many chemicals as you thought but this is a big one. Titanium dioxide, as it turns out, is used in everything from toothpaste to mayonnaise to skim milk. If you’re not getting it from Twinkies, you’re getting it from somewhere.