Wrinkles: Menopause is also responsible for loss of firmness. Therefore, during menopause, women can experience the appearance of wrinkles at this stage. This change is caused by the loss of estrogen. Surprisingly, women lose 30% of their collagen in the first 5 years of menopause. Estrogen has a protective effect on skin including protecting our skin from photoaging. Therefore, when the body loses its capacity to produce estrogen, our skin loses its capacity to protect itself against damaging elements, thus increasing the appearance of wrinkles. During menopause, age-related deterioration accelerates. The results include thinner skin, the increase in both the number and depth of wrinkles, and decreased elasticity of the skin.