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11. Moving
You take a new job or relocate to a different neighborhood and it’s more than used furniture you leave behind. Friendships are hard to maintain when distance and new interests pull you apart.

12. Marriage
She was your best friend in college and maid of honor at your wedding, but your husband can’t stand to be in the same room with her. You and your spouse start cultivating other couples as friends and you and your BFF drift apart.