5. There is no more room for growth.
If you’re in a dead end position and none of your co-workers have been promoted in 10 years, move on before you end up looking like the freakish balding guy in the corner cubicle.

6. No amount of money seems to make it worth your misery.
You’re so unhappy at work that you can’t enjoy the fruits of your labor and you put off vacations because it seems more painful to taste freedom and have to go back than to just keep your nose to the grindstone.