If you start feeling like a human water fountain—copious diarrhea, vomiting, fever—it’s time to see a doctor. Antibiotics work, but not for all strains. Some E. coli, like the dreaded O157:H7, get angry when you give them antibiotics. They release more toxins. So don’t play doctor. Let the lab coat folks handle it.
Funny note: The famous "Montezuma’s Revenge" is often from E. coli. That name makes it sound like a tropical vacation gone wrong. It’s not a vacation. It’s a biological mutiny. Respect the mutiny.